Clinical Trials Directory

Trials / Withdrawn

WithdrawnNCT04126044

A SINGLE-DOSE, 2-ARM, PHARMACOKINETIC STUDY OF PF-06439535 (CN) AND EUROPEAN UNION SOURCED BEVACIZUMAB IN CHINESE HEALTHY MALE VOLUNTEERS

A DOUBLE BLIND, RANDOMIZED, PARALLEL-GROUP, SINGLE-DOSE, 2-ARM, COMPARATIVE PHARMACOKINETIC STUDY OF PF-06439535 (CN) AND BEVACIZUMAB SOURCED FROM EUROPEAN UNION ADMINISTERED TO CHINESE HEALTHY MALE VOLUNTEERS

Status
Withdrawn
Phase
Phase 1
Study type
Interventional
Enrollment
0 (actual)
Sponsor
Pfizer · Industry
Sex
Male
Age
21 Years – 55 Years
Healthy volunteers
Accepted

Summary

This is a double-blind, randomized (1:1), parallel group, single dose, 2-arm, comparative PK study of PF-06439535 (CN) and bevacizumab-EU administered intravenously to Chinese healthy male volunteers. Approximately 66 subjects will be enrolled to ensure that at least 58 subjects (29 per arm) complete the study procedures and have evaluable PK data. The study will be conducted at 1 center in China.

Conditions

Interventions

TypeNameDescription
DRUGPF-06439535 (CN)This is the test drug Pfizer biosimilar of bevacizumab-EU.
DRUGbevacizumab - EUThis is the reference drug bevacizumab sourced from EU

Timeline

Start date
2021-01-22
Primary completion
2021-07-10
Completion
2021-07-10
First posted
2019-10-14
Last updated
2021-04-27

Locations

1 site across 1 country: China

Source: ClinicalTrials.gov record NCT04126044. Inclusion in this directory is not an endorsement.