NCT04125875

Gastric Slow Wave and Autonomic Nervous Function in Cirrhotic Patients With Esophageal Varices After Ligation-A Clinical Research

Gastric Slow Wave and Autonomic Nervous Function in Cirrhotic Patients With

• Status: Completed
• Phase: —
• Study type: Observational
• Enrollment: 28 (actual)
• Sponsor: The First Affiliated Hospital with Nanjing Medical University · Academic / Other
• Sex: All
• Age: 18 Years
• Healthy volunteers: Not accepted

Summary

This study is intended to include 20 patients with esophageal varices caused by liver cirrhosis who were admitted to the first affiliated hospital of nanjing medical university from May 2019, and randomly select 8 patients with gastric polyps as the control group.General clinical data, imaging data, endoscopic data and laboratory indicators were collected.Electrogastrogram (EGG) and Heart Rate Variability (HRV) were performed before and 24 hours after operation in patients with cirrhotic esophageal varices, and the dyspepsia scale was filled out.Electrogastrogram (EGG) and cardiac variability (HRV) were performed in patients with gastric polyps 24 hours before and after surgery, and the dyspepsia scale was filled.EGG uses the surface electrode to record gastric myoelectric activity, and evaluates the patient's gastric rhythm by normal slow wave ratio, overspeed ratio, overslow ratio, and rhythm disorder ratio.The HRV evaluates the balance state of the patient's autonomic nervous system with High Frequency (HF)/Low Frequency (LF).SPSS software was used for paired sample analysis of experimental results.

Conditions

• Esophageal Varices in Cirrhosis of the Liver

Interventions

Type	Name	Description
DIAGNOSTIC_TEST	Electrogastrogram(EGG)	Heart Rate Variability
DIAGNOSTIC_TEST	Heart Rate Variability(HRV)	Heart Rate Variability

Timeline

• Start date: 2019-05-23
• Primary completion: 2019-07-24
• Completion: 2019-07-31
• First posted: 2019-10-14
• Last updated: 2019-10-14

Locations

1 site across 1 country: China