NCT04118816

Autonomic Regulation in Prader-Willi Syndrome

Impact of Sleep-disordered Breathing on Autonomic Regulation in Patients With Prader-Willi Syndrome

• Status: Unknown
• Phase: —
• Study type: Observational
• Enrollment: 120 (estimated)
• Sponsor: Taipei Tzu Chi Hospital, Buddhist Tzu Chi Medical Foundation · Academic / Other
• Sex: All
• Age: 7 Years – 75 Years
• Healthy volunteers: Accepted

Summary

To evaluate autonomic regulation in patients with Prader-Willi syndrome with sleep-disordered breathing.

Detailed description

To evaluate the relationship between narcolepsy and sleep-disordered breathing, the natural course of untreated or treated sleep-disordered breathing and its impacts on autonomic regulation in patients with Prader-Willi syndrome with sleep-disordered breathing.

Conditions

• Autonomic Dysfunction

Interventions

Type	Name	Description
DIAGNOSTIC_TEST	Polysomnography	overnight polysomnography recording at least six hours
DIAGNOSTIC_TEST	Multiple sleep latency test	daytime naps at least four to five naps to evaluate daytime sleepiness and narcolepsy
OTHER	Continuous positive airway pressure	continuous positive airway pressure treatment for sleep-disordered breathing

Timeline

• Start date: 2019-06-25
• Primary completion: 2022-07-31
• Completion: 2022-07-31
• First posted: 2019-10-08
• Last updated: 2019-10-15

Locations

1 site across 1 country: Taiwan