Clinical Trials Directory

Trials / Unknown

UnknownNCT04115982

Vitamin D3 in Sensory Recovery After Digital NERVe Suture (D3NERV).

Vitamin D3 in Sensory Recovery After Digital NERVe Suture: a Randomized Controlled Trial.

Status
Unknown
Phase
Phase 3
Study type
Interventional
Enrollment
72 (estimated)
Sponsor
University Hospital, Caen · Academic / Other
Sex
All
Age
18 Years – 51 Years
Healthy volunteers
Not accepted

Summary

Digital nerve injuries are frequent in a FESUM center (Federation Européenne des Services d'Urgences Mains), and they need to be repaired in order to reduce the risk of hypoesthesia and to prevent painful neuroma. Several animal studies have shown that Cholecalciferol improves axonal nerve regeneration and myelination. No study has ever been done on human subjects to evaluate the nerve regeneration after Cholecalciferol supplementation. Our hypothesis is that Cholecalciferol supplementation could improve axonal nerve regeneration and myelination after traumatic digital nerve injuries treated by microsurgical sutures and reduce the risk of hypoesthesia and neuroma.

Conditions

Interventions

TypeNameDescription
DRUGCholecalciferolOne vial every 15 days during 2 months
DRUGPlacebosOne vial every 15 days during 2 months

Timeline

Start date
2020-01-20
Primary completion
2022-12-01
Completion
2022-12-01
First posted
2019-10-04
Last updated
2021-08-31

Locations

3 sites across 1 country: France

Source: ClinicalTrials.gov record NCT04115982. Inclusion in this directory is not an endorsement.