NCT04114435

Pulmonary Vascular Disease and Cardiac Performance in Extreme Preterm Infants

Pulmonary Vascular Disease and Cardiac Performance in Extreme Preterm Infants: A Prospective Cross-sectional Study

• Status: Recruiting
• Phase: —
• Study type: Observational
• Enrollment: 150 (estimated)
• Sponsor: McGill University Health Centre/Research Institute of the McGill University Health Centre · Academic / Other
• Sex: All
• Age: 7 Days – 5 Years
• Healthy volunteers: Accepted

Summary

Pulmonary vascular disease and cardiac performance in extreme preterm infants: A prospective cross-sectional study

Detailed description

The principal investigator hypothesize that premature newborns have disturbed cardiac performance and increased pulmonary pressures during neonatal life and at different pediatric ages. The principal investigator also hypothesize that premature newborns with poor cardiac performance and/or pulmonary hypertension have higher morbidities and poorer neuro-developmental outcomes. The principal investigator also hypothesize that premature newborns with poor cardiac performance and/or pulmonary hypertension have higher morbidities and poorer neuro-developmental outcomes and that novel echocardiography techniques will detect anomalies not uncovered by conventional imaging, and that early echocardiography may identify those with later pulmonary hypertension.

Conditions

• Prematurity; Extreme

Interventions

Type	Name	Description
OTHER	Echocardiography	Diagnostic test which uses ultrasound waves to make images of the heart chambers, valves and surrounding structures

Timeline

• Start date: 2019-10-12
• Primary completion: 2023-11-30
• Completion: 2025-12-01
• First posted: 2019-10-03
• Last updated: 2025-06-17

Locations

1 site across 1 country: Canada