Trials / Completed
CompletedNCT04114097
The Effects of Topical Corticosteroid Use on Insulin Sensitivity and Bone Turnover
- Status
- Completed
- Phase
- Phase 4
- Study type
- Interventional
- Enrollment
- 36 (actual)
- Sponsor
- Jacob Thyssen · Academic / Other
- Sex
- All
- Age
- 18 Years – 75 Years
- Healthy volunteers
- Not accepted
Summary
The investigators believe that the emerging epidemiological evidence connecting topical use of corticosteroids to the development of type 2 diabetes and osteoporosis point to potentially massive, yet clinically unacknowledged problems associated with topical corticosteroid treatment. Using state-of-the-art methodology, the present study will delineate the impact of topical corticosteroid use on insulin sensitivity and bone turnover markers in patients with atopic dermatitis and, thus, provide important data that may have implications for millions of people using topical corticosteroids.
Conditions
Interventions
| Type | Name | Description |
|---|---|---|
| DRUG | Betnovate, betamethasone dipropionate ointment 0.1% and placebo | Explore the systemic effects of Betnovate |
| DRUG | Protopic, tacrolimus ointment 0.1% | Compare the systemic effects of Betnovate to Protopic |
Timeline
- Start date
- 2019-08-22
- Primary completion
- 2021-03-15
- Completion
- 2021-03-15
- First posted
- 2019-10-03
- Last updated
- 2021-04-28
Locations
1 site across 1 country: Denmark
Source: ClinicalTrials.gov record NCT04114097. Inclusion in this directory is not an endorsement.