NCT04111406

Comparison of the Incidence of Inadequate Epidural Analgesia Between Protocol Based and Current Practice

• Status: Terminated
• Phase: N/A
• Study type: Interventional
• Enrollment: 29 (actual)
• Sponsor: Mahidol University · Academic / Other
• Sex: All
• Age: 18 Years
• Healthy volunteers: Accepted

Summary

Epidural analgesia is the recommended analgesic technique in patients having surgery with severe postoperative pain such as thoracic and upper abdominal surgery. However, from the previous study, the incidence of inadequate pain control in patients receiving epidural analgesia is very high 48.6% in our hospital.

Detailed description

A high incidence of inadequate epidural analgesia may result from variety of epidural techniques and epidural drug administrations. The protocol based practice has been developed from acute pain service which founded for more than 10 years. By using protocol based practice, the investigators believed that the incidence of inadequate epidural analgesia will be less compared with the current practice.

Conditions

• Epidural Analgesia
• Postoperative Pain

Interventions

Type	Name	Description
DRUG	Current practice	Epidural insertion and epidural drug administration depend on anesthetist in charge
DRUG	Protocol based	Epidural insertion and epidural drug administration depend on anesthetist in research team using protocol based 1. insertion at mid-level of surgical insertion 2. insertion depth is 3-5 cm in space, not more than 5 cm 3. using benzoin tincture and transparent dressing to fix catheter 4. test dose with 2%xylocaine with adrenaline 1:200,000 3ml If not cover desired dermatome: 2% lidocaine with adr added 3 ml every 5 min (up to 2 times) 5. After induction and patients' hemodynamic are stable. Load 2 mg morphine with 0.0625% bupivacaine + morphine 0.02 mg/ml 3 ml then continuous infusion with rate according to initial local anesthetic requirement for incisional area coverage

Timeline

• Start date: 2019-01-09
• Primary completion: 2021-10-28
• Completion: 2021-10-28
• First posted: 2019-10-01
• Last updated: 2022-07-26

Locations

1 site across 1 country: Thailand