NCT04111328

the Effect of Different Drugs and Infusion Ways on Degree of Postoperative Comfort

the Effect of Different Drugs and Infusion Ways on Degree of Comfort for Patients Undergoing Spinal Neoplasm Surgery

• Status: Completed
• Phase: Phase 4
• Study type: Interventional
• Enrollment: 600 (actual)
• Sponsor: Jun Wang · Academic / Other
• Sex: All
• Age: 18 Years – 65 Years
• Healthy volunteers: Not accepted

Summary

To explore the effect of different drugs and infusion ways on degree of postoperative comfort.Patients undergoing spinal neoplasm surgery receive different patient controlled analgesia(PCA) drugs postoperatively,one group is sufentanil,the other is hydromorphone. Then each drug group will be divided into two subgroups according to the infusion way,intravenously,subcutaneously. During the patient controlled analgesia period, patients' degree of comfort,pain score,sleep quality, the degree of side reaction will be recorded.

Conditions

• Analgesia, Patient-Controlled

Interventions

Type	Name	Description
DRUG	intravenous sufentanil	The PCA pumps contain sufentanil . And the pump is connected to participants intravenously .
DRUG	subcutaneous sufentanil	The PCA pumps contain sufentanil. And the pump is connected to participants subcutaneously.
DRUG	intravenous hydromorphone	The PCA pumps contain hydromorphone. And the pump is connected to participants intravenously .
DRUG	subcutaneous hydromorphone	The PCA pumps contain hydromorphone. And the pump is connected to participants subcutaneously.
DRUG	intravenous sufentanil and dexmedetomidine	The PCA pumps contain sufentanil and dexmedetomidine. And the pump is connected to participants intravenously .
DRUG	subcutaneous sufentanil and dexmedetomidine	The PCA pumps contain sufentanil and dexmedetomidine. And the pump is connected to participants subcutaneously.
DRUG	intravenous hydromorphone and dexmedetomidine	The PCA pumps contain hydromorphone and dexmedetomidine. And the pump is connected to participants intravenously.
DRUG	subcutaneous hydromorphone and dexmedetomidine	The PCA pumps contain hydromorphone and dexmedetomidine. And the pump is connected to participants subcutaneously

Timeline

• Start date: 2019-10-08
• Primary completion: 2020-09-30
• Completion: 2020-10-30
• First posted: 2019-10-01
• Last updated: 2021-02-09

Locations

1 site across 1 country: China