NCT04110782

Radical Prostatectomy and External Beam Radiotherapy in mCRPC With 223Radium-dicloride (RaProRad)

Evaluation of Previeus Radical Prostatectomy and/or External Beam Radiotherapy as Protective Factors in mCRPC Patients Treated With 223Radium-dicloride and Correlation With Overall Survival: an Italian Multicenter Study

• Status: Unknown
• Phase: —
• Study type: Observational
• Enrollment: 400 (estimated)
• Sponsor: Azienda Policlinico Umberto I · Academic / Other
• Sex: Male
• Age: —
• Healthy volunteers: Not accepted

Summary

The investigators provided a multicenter analysis aiming to investigate, in a clinical practice setting, the prognostic relevance of previous primary radical prostatectomy (RP) or external beam radiotherapy (RT) in terms of Overall Survival as opposed to patients with no primary treatment performed, in a cohort of patients enrolled in 223-Ra treatment for mCRPC. 223-Ra has been administered from investigators according to the current label authorization and all patients underwent 223-Ra treatment, until disease progression or unacceptable toxicity.

Conditions

• Prostate Cancer

Interventions

Type	Name	Description
OTHER	Radium223	55 kBq/ Kg

Timeline

• Start date: 2015-09-01
• Primary completion: 2019-06-01
• Completion: 2020-01-01
• First posted: 2019-10-01
• Last updated: 2019-10-01

Locations

1 site across 1 country: Italy