NCT04110535

Abuse Potential of Intravenous Remimazolam Compared to Midazolam and Placebo in Recreational CNS Depressant Users

A Double-blind, Randomized Crossover Study to Assess the Subjective Abuse Potential of Intravenous Remimazolam Compared to Midazolam and Placebo in Recreational CNS Depressant Users

• Status: Completed
• Phase: Phase 1
• Study type: Interventional
• Enrollment: 83 (actual)
• Sponsor: Paion UK Ltd. · Industry
• Sex: All
• Age: 18 Years – 55 Years
• Healthy volunteers: Accepted

Summary

A double-blind, randomized crossover study to assess the subjective abuse potential of intravenous remimazolam compared to midazolam and placebo in recreational CNS depressant users

Conditions

• Abuse, Drug

Interventions

Type	Name	Description
DRUG	Remimazolam	IV administration over 1 minute
DRUG	Midazolam	IV administration over 1 minute
OTHER	Saline	IV administration over 1 minute

Timeline

• Start date: 2015-06-23
• Primary completion: 2015-10-06
• Completion: 2015-10-06
• First posted: 2019-10-01
• Last updated: 2019-10-01

Locations

1 site across 1 country: United States

Regulatory

• FDA-regulated drug study