NCT04109846

Pregnancy and Developmental Outcomes After Transfer of Reportedly Aneuploid or Mosaic Embryos

Transfer of Aneuploid or Mosaic Embryos Following Preimplantation Genetic Testing

• Status: Recruiting
• Phase: N/A
• Study type: Interventional
• Enrollment: 300 (estimated)
• Sponsor: Stanford University · Academic / Other
• Sex: Female
• Age: 18 Years – 55 Years
• Healthy volunteers: Accepted

Summary

To determine how often embryos reported to be abnormal by preimplantation genetic testing result in liveborn infants. To evaluate whether the pregnancies that result from these embryos are higher risk for complications and whether the resulting babies have higher risk for health or developmental issues in the first five years after birth.

Detailed description

Genetic testing modality and results will be recorded Pregnancy per transfer will be recorded Patients in the study agree to provide medical records of their pregnancy. Any genetic testing or fetal testing will be carefully reviewed and recorded by the study team. For patients with live births, pediatric records will be collected for up to 5 years. As well as surveys for developmental milestones. There is no financial compensation for study participants

Conditions

• Aneuploidy
• Mosaicism
• Pregnancy Outcome

Interventions

Type	Name	Description
OTHER	Non-euploid embryo transfer	Other than choice of embryo for transfer, all other medical interventions will be standard of care protocols
OTHER	Euploid Transfer	Standard of Care Protocol

Timeline

• Start date: 2019-04-11
• Primary completion: 2035-04-01
• Completion: 2039-04-01
• First posted: 2019-09-30
• Last updated: 2025-04-03

Locations

1 site across 1 country: United States