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Active Not RecruitingNCT04106219

A Study of LY3295668 Erbumine in Participants With Relapsed/Refractory Neuroblastoma

A Phase 1 Study of Aurora Kinase A Inhibitor LY3295668 Erbumine as a Single Agent and in Combination in Patients With Relapsed/Refractory Neuroblastoma

Status
Active Not Recruiting
Phase
Phase 1
Study type
Interventional
Enrollment
71 (estimated)
Sponsor
Eli Lilly and Company · Industry
Sex
All
Age
2 Years – 21 Years
Healthy volunteers
Not accepted

Summary

The reason for this study is to see if the study drug LY3295668 erbumine is safe in participants with relapsed/refractory neuroblastoma.

Conditions

Interventions

TypeNameDescription
DRUGLY3295668 ErbumineAdministered orally.
DRUGTopotecanAdministered IV.
DRUGCyclophosphamideAdministered IV.

Timeline

Start date
2020-06-11
Primary completion
2022-04-13
Completion
2026-08-01
First posted
2019-09-26
Last updated
2025-07-23

Locations

17 sites across 9 countries: United States, Australia, Belgium, France, Germany, Italy, Japan, Spain, United Kingdom

Regulatory

Source: ClinicalTrials.gov record NCT04106219. Inclusion in this directory is not an endorsement.