NCT04103320

Evaluation of Pain in the Course of in Vitro Fertilization

Evaluation of Pain in the Course of in Vitro Fertilization: the Endalgofiv Study

• Status: Completed
• Phase: —
• Study type: Observational
• Enrollment: 318 (actual)
• Sponsor: University Hospital, Lille · Academic / Other
• Sex: Female
• Age: 18 Years – 43 Years
• Healthy volunteers: Not accepted

Summary

25 to 50% of endometriotic patients are infertile and use medically assisted procreation. In general, the assessment of pain in medically assisted procreation is very little studied. Pain assessment studies in endometriotic patients remain limited to a quantitative assessment of pain symptomatology, without contextualization of painful manifestations. The primary objective of our study is the qualitative and contextualized assessment of pain during In Vitro Fertilization (IVF) protocol in endometriotic and non-endometriotic patients. The secondary objectives of our study are the quantitative study of pain, the measurement of the impact of personal efficiency on painful symptomatology, evaluation of depression, the results of IVF (implantation, pregnancy and live birth rates), and compare pain between endometriotic or non-endometriotic patients and between primary infertility and secondary infertility. According to the results obtained in this study, therapeutic strategies for the management of pain could be proposed, with the aim of improving the quality of life and the results of IVF in these patients.

Conditions

• Infertility

Interventions

Type	Name	Description
OTHER	Using different survey to evaluate pain	Survey will be at different time of the IVF protocol (at the first medical appointment in the medically assisted department, after stimulation, after oocytes retrieval, after embryo transfer, one month after the IVF protocol)

Timeline

• Start date: 2019-11-18
• Primary completion: 2021-08-04
• Completion: 2021-08-04
• First posted: 2019-09-25
• Last updated: 2022-04-29

Locations

1 site across 1 country: France