NCT04098133

Epidemiology of Carbapenemase-producing Bacteria in a Swiss Tertiary Care Hospital

• Status: Recruiting
• Phase: —
• Study type: Observational
• Enrollment: 100 (estimated)
• Sponsor: University Hospital, Basel, Switzerland · Academic / Other
• Sex: All
• Age: 18 Years
• Healthy volunteers: Not accepted

Summary

This retrospective and prospective study is to investigate the incidence of Carbapenemase-producing bacteria (CPB) at the University Hospital Basel, the time to detection of CPB and to initiation of infection control measures, the risk factors associated with carriage of CPB, type and duration of previously administrated antibiotic medication, antibiotic treatment, as well as to assess the outcomes of the affected patients.

Conditions

• Infections With CPB

Interventions

Type	Name	Description
OTHER	data collection for demographic data	data collection for demographic data (age, gender, hospital admission and discharge date, length of stay, hospitalization prior to current hospital stay (acute care facilities, long-term healthcare centres, nursing homes), discharge destination, outcome, cause of death, travel history, previous exposure to antibiotics and proton pump Inhibitors)
OTHER	data collection for clinical data	data collection for clinical data (comorbidities, Charlson Comorbidity Index, immunosuppressive treatment, date of diagnosis of CPB, days between hospital admission and diagnosis of CPB, type of consecutive infection, indwelling vascular hardware, urinary catheterization, surgical therapies)
OTHER	data collection for treatment data	data collection for treatment data (antibiotic therapy, immunosuppressive therapy, concomitant medication)
OTHER	data collection for microbiological data	data collection for microbiological data (species of CPB, type of sample, date of sample, history of colonization or infection with any antibiotic resistant pathogen)

Timeline

• Start date: 2019-08-22
• Primary completion: 2029-06-30
• Completion: 2029-06-30
• First posted: 2019-09-23
• Last updated: 2024-12-13

Locations

1 site across 1 country: Switzerland