NCT04097899

Antimicrobial Stewardship Program and Ventilator Associated Pneumonia

Impact of Implementation of Antimicrobial Stewardship Comprehensive Care Bundle Program on Ventilator Associated Pneumonia in Surgical Intensive Care Unit

• Status: Completed
• Phase: —
• Study type: Observational
• Enrollment: 25 (actual)
• Sponsor: Zagazig University · Other Government
• Sex: All
• Age: 18 Years – 70 Years
• Healthy volunteers: Not accepted

Summary

Antibiotic Stewardship Programs (ASPs) help clinicians improve the quality of patient care and improve patient safety through increased infection cure rates, reduced treatment failures; however, there are different techniques, with variable results, of its application including what is called ASPs bundle and there is a need to investigate the effectiveness of implementing a comprehensive care bundle program including the key components of ASPs and the key items of infection control measures, this program can be called Antimicrobial Stewardship Comprehensive Care Bundle Program (ASCCBP).

Detailed description

Survey experimental study will be done in the first 6 months as regard antimicrobial drugs pattern and organism's sensitivity and resistance pattern in VAP patients. In the next six months, clinical implementation of ASPs and infection control bundle will be applied on VAP patients. Then, in the later six months the investigators will study the outcome of VAP patients as regard: * Amount of cost of antibiotics. * Appropriates of antibiotic use (initiation, duration \& time of discontinuation). * Rate of resistance * Clinical outcome, infection rate \&length of stay. Regular reports on antibiotic use and resistance will be admitted to relevant staff every one month. Also, audit and feedback about resistance and optimal prescribing will be applied every one month for ICU stuff as an open discussion. The stewardship consulting team will include microbiologist with clinical experience in the field of antibiotic use and infection control. Stewardship team also will include the relevant ICU staff and an experienced clinical pharmacist.

Conditions

• Ventilator Associated Pneumonia

Interventions

Type	Name	Description
OTHER	implementation of antimicrobial stewardship comprehensive care bundle program on ventilator associated pneumonia patients	Construction of a comprehensive care bundle educational program. This program consisted of many elements: Antimicrobial stewardship programs, VAP bundles and infection control policy implementation and the investigators studied the impact of this program on: * Antibiotics cost. * Appropriates of antibiotic use (initiation, duration \& time of discontinuation). * Rate of resistance * Clinical outcome, infection rate \&length of stay.

Timeline

• Start date: 2016-07-01
• Primary completion: 2017-12-31
• Completion: 2017-12-31
• First posted: 2019-09-20
• Last updated: 2019-09-20