NCT04097886

Timed Exercise Study

Investigating the Effects of Timed Exercise on Human Circadian Rhythms

• Status: Completed
• Phase: N/A
• Study type: Interventional
• Enrollment: 67 (actual)
• Sponsor: Julie Pendergast · Academic / Other
• Sex: All
• Age: 18 Years – 45 Years
• Healthy volunteers: Accepted

Summary

The purpose of this study was to investigate the effect of timed exercise on human circadian rhythms. Subjects were randomized to 5 days of morning or evening treadmill exercise. A measure of internal circadian timing, or phase, was measured at baseline and following the exercise intervention. Change in circadian phase was compared between the morning and evening group.

Detailed description

This study investigated the effect of morning versus evening exercise on internal circadian timing, or phase. Young, sedentary subjects were recruited for this study. Baseline measures included anthropometric, body composition, cardiorespiratory fitness, chronotype, and circadian phase. Subjects were randomized to 5 consecutive days of morning or evening exercise. Thirty minutes of exercise was performed at the designated time and intensity was maintained at a heart rate corresponding with 70% peak VO2. The measure of circadian phase was salivary dim light melatonin onset, indicated by the time when saliva melatonin concentration exceeded 4pg/ml. Post-exercise circadian phase was measured the evening following the last day of exercise. Changes in circadian phase were compared between morning and evening groups.

Conditions

• Circadian Timing - Exercise

Interventions

Type	Name	Description
OTHER	Morning Exercise	moderate intensity exercise (70% VO2 max) each morning for 5 days
OTHER	Evening Exercise	moderate intensity exercise (70% VO2 max) each evening for 5 days

Timeline

• Start date: 2017-06-27
• Primary completion: 2019-03-09
• Completion: 2019-03-09
• First posted: 2019-09-20
• Last updated: 2019-09-20

Locations

1 site across 1 country: United States