Clinical Trials Directory

Trials / Completed

CompletedNCT04097847

Osteoradionecrosis and PENTOCLO Protocol: Retrospective Study

Osteoradionecrosis and PENTOCLO Protocol: Retrospective Study.

Status
Completed
Phase
Study type
Observational
Enrollment
96 (actual)
Sponsor
University Hospital, Brest · Academic / Other
Sex
All
Age
18 Years
Healthy volunteers
Not accepted

Summary

osteoradionecrosis (ORN) affects up to 30% of irradiated patients and can occur up to several decades after stopping treatment. Differents therapeutics exist but there is no consensus concerning the management of the maxillary ORN. The understanding of new pathological mechanisms opens the way to new therapeutic perspectives.

Conditions

Interventions

TypeNameDescription
DRUGPentoxifylline-Tocopherol-Clodronatethe aim of this retrospective study is to analyze from patient records the impact of the PENTOCLO protocol on maxillofacial osteoradionecrosis at Brest Hospital University, France.

Timeline

Start date
2017-06-02
Primary completion
2019-04-01
Completion
2019-04-01
First posted
2019-09-20
Last updated
2019-11-01

Locations

1 site across 1 country: France

Source: ClinicalTrials.gov record NCT04097847. Inclusion in this directory is not an endorsement.