NCT04096612

The Therapeutic Effect of Dysthyroid Optic Neuropathy

• Status: Unknown
• Phase: N/A
• Study type: Interventional
• Enrollment: 20 (estimated)
• Sponsor: Sun Yat-sen University · Academic / Other
• Sex: All
• Age: 18 Years – 70 Years
• Healthy volunteers: Accepted

Summary

Thyroid associated ophthalmopathy (TAO) is a common autoimmune disorder. The pathogenesis of TAO is unclear, and studies found that T cell, B cell and monocytes, macrophages and mast cells are located in the orbital tissue of TAO. Dysthyroid optic neuropathy (DON) is the most serious complication of TAO, which can cause blurred vision, color vision and vision function damage, and affects the quality of life. Investigation of the therapeutic effect of orbital decompression may provide some clues to make the policy at treatment of DON. We explore the therapeutic effect of orbital decompression in patients with DON in both eyes.

Conditions

• Thyroid Eye Disease

Interventions

Type	Name	Description
PROCEDURE	Orbital decompression combined with MPT	Orbital decompression combined with MPT

Timeline

• Start date: 2016-01-01
• Primary completion: 2018-12-31
• Completion: 2019-12-31
• First posted: 2019-09-20
• Last updated: 2019-09-20

Locations

1 site across 1 country: China