NCT04094753

Think Dry: Optimalisation of Diagnostic Process of Urinary Incontinence in Older People

• Status: Unknown
• Phase: —
• Study type: Observational
• Enrollment: 202 (estimated)
• Sponsor: University Hospital, Ghent · Academic / Other
• Sex: All
• Age: 65 Years
• Healthy volunteers: Not accepted

Summary

Urinary incontinence is an increasing medical and socio-economical problem. 44% of the elderly (\>65 years) women and 28% of the elderly men suffer from unwilling urine loss. Moreover, this percentages increase with age. Incontinence is a problem with multiple physical, psychological, and financial effects. In addition incontinence has a important impact on the family and healthcare professionals surrounding the elderly. The problem of urinary incontinence is complex and multifactorial. Moreover, diagnostic guidelines are inconsistent leading to a high amount of technical interventions to diagnose and to specify the type of incontinence. Aim of this study is to create a short form of necessary technical investigations to diagnose and evaluate urinary incontinence.

Conditions

• Incontinence, Urge
• Incontinence Stress
• Incontinence, Daytime Urinary
• Incontinence, Nighttime Urinary

Interventions

Type	Name	Description
DIAGNOSTIC_TEST	Blood Sample	A sober blood sample is taken to observe the following parameters: creatinin, ureum, sodium, potassium, osmolality, HDL cholesterol, LDL cholesterol, triglycerides)
DIAGNOSTIC_TEST	Renal Function Profile	A Renal Function Profile is a 24 hour-urine collection in which urine samples are collected at fixed time points every 3 hours, starting 3 hours after the first morning void. Daytime samples were taken at 10:00-11:30 (U1), 13:00-15:30 (U2), 16:00-17:30 (U3), 19:00-20:30 (U4), and 22:00-23:30 (U5). The nighttime samples were taken at 1:00-2:30 (U6), 4:00-5:30 (U7) and 7:00-8:30 (U8). The volume of each sample, and of each micturition in between, was noted to calculate the 24h, daytime and nighttime urine volume and diuresis rate.
DIAGNOSTIC_TEST	Frequency Volume Chart	Every patient complets a frequency volume chart during 24 of 72 hours
DIAGNOSTIC_TEST	Cystometry	This technique provide the most precise measurement of bladder and urethral sphincter behaviour during bladder filling and during voiding.
DIAGNOSTIC_TEST	Questionaires	Patients have to fulfill the following questionaires * ICIQ-Fluts for female participants or ICIQ-Mluts for male participants * TILBURG FRAILTY INDICATOR * SF-36 Quality of Life score * N- QOL
DIAGNOSTIC_TEST	Flow rate measurement + Observation of the post-void residual urine volume	A measurement of the urinary flow rate is observed to collect the maximum Q/s. Afterwards an observation of the PVR is done using ultrasound.
DIAGNOSTIC_TEST	Clinical Examination	Clinical examination of the genital region. For women, coeles are described using the POPQ

Timeline

• Start date: 2014-01-01
• Primary completion: 2024-08-01
• Completion: 2024-08-01
• First posted: 2019-09-19
• Last updated: 2024-01-31

Locations

1 site across 1 country: Belgium