NCT04093843

TMS for Post Stroke Depression

Accelerated rTMS as a Treatment for Post-stroke Depression in the Subacute Phase: an Open Label Pilot Study

• Status: Completed
• Phase: N/A
• Study type: Interventional
• Enrollment: 6 (actual)
• Sponsor: Amelia Adcock · Academic / Other
• Sex: All
• Age: 22 Years – 85 Years
• Healthy volunteers: Not accepted

Summary

The purpose of this study is to find alternative treatments for patient's suffering from depression after having a stroke.This study aims to show that accelerated rTMS is a safe, effective,and convenient treatment for patient's suffering from post-stroke depression in the acute to subacute phase. This will be an open label trial and thus all participants will receive the active rTMS intervention.

Detailed description

The primary objectives of this project are as follows: 1. To assess the efficacy TMS in PSD. We hypothesize that there will be a decrease in the HAMD score in patients receiving TMS 2. To assess the feasibility of an accelerated protocol using rTMS in patients with acute to subacute stroke and co-existing PSD. We hypothesize that the accelerated protocol will promote compliance in our patient population and that the administration of this intervention is feasible. 3. To assess the safety of rTMS in patients with acute to subacute stroke. We hypothesize that the side effects of TMS will be minimal and the therapy will be well-tolerated and safe in individuals with recent strokes and co-existing PSD.

Conditions

• Post-stroke Depression

Interventions

Type	Name	Description
DEVICE	TMS	NeuroStar TMS Therapy

Timeline

• Start date: 2018-10-24
• Primary completion: 2020-06-30
• Completion: 2020-06-30
• First posted: 2019-09-18
• Last updated: 2022-04-29
• Results posted: 2022-04-29

Locations

1 site across 1 country: United States

Regulatory

• FDA-regulated device study