NCT04090801

Comparison of Topical Minoxidil 5% in Ethanol Plus Propylene Glycol Versus Minoxidil 5% in Ethanol Alone in Treatment of Women With Female Pattern Hair Loss

Minoxidil in Treatment of Androgenetic Alopecia

• Status: Completed
• Phase: Phase 4
• Study type: Interventional
• Enrollment: 60 (actual)
• Sponsor: Sohag University · Academic / Other
• Sex: Female
• Age: 20 Years – 60 Years
• Healthy volunteers: Accepted

Summary

The study will be included 60 women with FPHL. The diagnosis of FPHL will be established by clinical (Ludwig classification) and trichoscopic evaluation of frontal and occipital regions of the scalp.

Detailed description

Enrolled women will be randomly assigned into 3 treatment groups: group A will apply topical minoxidil 5% in 90% ethanol and 5% propylene glycol, group B will apply topical minoxidil 5% in pure ethanol alone and group C will apply pure ethanol (placebo) twice daily. The treatment will be continued for six months with regular visits at 3 months intervals. The medications will be provided in bottles which were identical in shape and color, and were coded by a third party. Both patients and investigator will be blinded to the medication. Disclosure of the codes will be done, by a third party, at the end of the study.

Conditions

• Female Pattern Hair Loss

Interventions

Type	Name	Description
DRUG	Topical minoxidil 5% in 90% ethanol and 5% propylene glycol
DRUG	Topical minoxidil 5% in pure ethanol alone	The treatment will be continued twice daily.for six months with regular visits at 3 months intervals.
OTHER	Placebo (Ethanol)	The treatment will be continued twice daily.for six months with regular visits at 3 months intervals.

Timeline

• Start date: 2015-05-30
• Primary completion: 2016-05-30
• Completion: 2017-01-23
• First posted: 2019-09-16
• Last updated: 2019-09-26