Clinical Trials Directory

Trials / Completed

CompletedNCT04090047

A Study to Investigate the Effect of Multiple Doses of Itraconazole on the Pharmacokinetics of PF-06700841 in Healthy Participants

A PHASE 1, OPEN-LABEL, FIXED SEQUENCE 2-PERIOD STUDY TO INVESTIGATE THE EFFECT OF MULTIPLE DOSES OF ITRACONAZOLE ON THE PHARMACOKINETICS OF A SINGLE DOSE OF PF-06700841 IN HEALTHY PARTICIPANTS

Status
Completed
Phase
Phase 1
Study type
Interventional
Enrollment
12 (actual)
Sponsor
Pfizer · Industry
Sex
All
Age
18 Years – 55 Years
Healthy volunteers
Accepted

Summary

An open-label, fixed-sequence, 2-period study to investigate the effect of multiple oral doses of itraconazole on a single oral dose of PF-06700841 PK in healthy participants. The study will consist of two treatment periods in one fixed sequence.

Conditions

Interventions

TypeNameDescription
DRUGPF-06700841PF-06700841 oral tablets in 5mg and 25mg provided for a 30mg dose
DRUGItraconazole200 mg oral solution administered as 20 milliliters(mL) (10 mg/mL)

Timeline

Start date
2019-09-24
Primary completion
2019-12-19
Completion
2019-12-19
First posted
2019-09-16
Last updated
2020-01-30

Locations

1 site across 1 country: United States

Regulatory

Source: ClinicalTrials.gov record NCT04090047. Inclusion in this directory is not an endorsement.