Trials / Completed
CompletedNCT04086511
PANDA: PKU Amino Acid Evaluation
PANDA: A Cross-sectional Study to Measure Blood Amino Acid Levels in PKU Children on a Protein Substitute
- Status
- Completed
- Phase
- —
- Study type
- Observational
- Enrollment
- 37 (actual)
- Sponsor
- Nutricia Research · Industry
- Sex
- All
- Age
- 2 Years – 12 Years
- Healthy volunteers
- —
Summary
Phenylketonuria (PKU) is a rare inherited metabolic disorder, where subjects are born with a genetic deficiency in the phenylalanine hydroxylase enzyme (PAH), which leaves them unable to convert Phenylalanine (Phe) into Tyrosine (Tyr). PKU patients have specific dietary needs and must follow a restrictive diet in the aim of preventing toxic levels of the amino acid phenylalanine (Phe) accumulation.
Detailed description
The exploratory study's main objective is to measure blood amino acid levels and to gain quantitative insights in children with PKU on a protein substitute with respect to evaluation of nutritional intake.
Conditions
Timeline
- Start date
- 2019-09-10
- Primary completion
- 2022-12-21
- Completion
- 2023-04-14
- First posted
- 2019-09-11
- Last updated
- 2023-06-02
Locations
2 sites across 2 countries: Belgium, United Kingdom
Source: ClinicalTrials.gov record NCT04086511. Inclusion in this directory is not an endorsement.