NCT04086498

Effects of a Ketogenic Diet on Psychological Outcomes

Effects of Ketonemia and Glycemia Variations During Ketogenic and Mediterranean Weight Loss Diets on Appetite Levels, Executive Functions and Mood

• Status: Completed
• Phase: N/A
• Study type: Interventional
• Enrollment: 50 (actual)
• Sponsor: University of Padova · Academic / Other
• Sex: Female
• Age: 20 Years – 35 Years
• Healthy volunteers: Accepted

Summary

The aim of the study is to investigate how glycemia and ketonemia variations during three different diet protocols: a ketogenic diet without any restriction on calories intake (KD), a calorie-restricted ketogenic-mediterranean diet (KEMEPHY) and a calorie-restricted mediterranean diet (MD) affect appetite, executive functions and mood in overweight young women.

Detailed description

Fifty overweight young women with a body mass index (BMI) greater than 25 will be randomly assigned to a ten days of ketogenic diet (KD), calorie-restricted ketogenic-mediterranean diet (KEMEPHY) or Mediterranean diet (MD). All subjects will begin the prescribed diet at the beginning of their follicular phase. Body composition, fasting blood glucose and β-hydroxybutyrate (BHB), visual analogue scale (VAS) to test appetite as well as psychological tests (one mood test and two cognitive tasks) will be obtained 5 days before the beginning and on the last day of the diet-period.

Conditions

• Overweight
• Mood
• Appetitive Behavior

Interventions

Type	Name	Description
OTHER	Mediterranean diet	The group received a plan for a isocaloric Mediterranean Diet
OTHER	KEMEPHY	The group received a plan for a ketogenic mediterranean with herbal extracts diet
OTHER	KD	The group received a plan for a low carbohydrate ketogenic diet

Timeline

• Start date: 2015-04-01
• Primary completion: 2016-04-30
• Completion: 2016-06-15
• First posted: 2019-09-11
• Last updated: 2019-09-11

Locations

1 site across 1 country: Italy