NCT04080388

How to Prevent Heart Failure Readmission by Using Lung Impedance Device (HOPE-HF Study)

• Status: Unknown
• Phase: Phase 3
• Study type: Interventional
• Enrollment: 200 (estimated)
• Sponsor: Hillel Yaffe Medical Center · Other Government
• Sex: All
• Age: 18 Years
• Healthy volunteers: Not accepted

Summary

The readmission of Heart Failure (HF) patients for exacerbation HF within 30-day is unmet goal. The mail reason for readmission is excessive accumulation of fluid in patient's lung. According our data (1,2) around 40% of HF patient have excessive lung fluid at discharge from HF hospitalization ("unacceptable" residual congestion on discharge). In other words, around 40% patients are discharged from HF hospitalization prematurely when they are not ready to be discharged. Only 60% of HF patients are discharged from HF admission with "acceptable" level of residual pulmonary congestion (2). There are some techniques to assess "readiness" of HF patients for discharge. Pulmonary congestion (lung fluid accumulation) may be assessed non-invasively by measurement Brain Natriuretic Peptide (BNP), (3,4), by lung ultrasound (LUS), (5-7) and by Lung Impedance (LI) method (1,2). LUS is operator depended technique. LI and BNP techniques are most reliable methods (2) and easy to use.

Conditions

• Heart Failure Acute

Interventions

Type	Name	Description
DIAGNOSTIC_TEST	Lung Impedance Device	The non-invasive lung impedance device enables assessment of the level of pulmonary congestion and can be an indication for additional anti-congestive treatment.
DRUG	Anti-congestive treatment	Continuation of in-hospital anti-congestive treatment

Timeline

• Start date: 2019-09-01
• Primary completion: 2021-09-01
• Completion: 2021-09-01
• First posted: 2019-09-06
• Last updated: 2019-09-06

Locations

1 site across 1 country: Israel