Clinical Trials Directory

Trials / Completed

CompletedNCT04080323

Single-dose Vaginal Dinoprostone and Hysterectomy

Effect of a Single Preoperative Dose of Vaginal Dinoprostone on Intraoperative Blood Loss During Abdominal Hysterectomy:a Randomized Controlled Trial

Status
Completed
Phase
Phase 3
Study type
Interventional
Enrollment
118 (actual)
Sponsor
Cairo University · Academic / Other
Sex
Female
Age
18 Years
Healthy volunteers
Not accepted

Summary

In this study, we will assess the efficacy of dinoprostone in minimizing blood loss during hysterectomy when used as a single preoperative dose via the vaginal route. The reduction of blood flow may be due to the combined effect of myometrial contraction and vasoconstrictive effect

Conditions

Interventions

TypeNameDescription
DRUGDinoprostone 3 mg1 vaginal tablet of 3mg dinoprostone 60 minutes before surgery
DRUGplacebo1 vaginal tablet of placebo 60 minutes before surgery

Timeline

Start date
2019-09-25
Primary completion
2020-05-30
Completion
2020-06-30
First posted
2019-09-06
Last updated
2020-08-27

Locations

1 site across 1 country: Egypt

Source: ClinicalTrials.gov record NCT04080323. Inclusion in this directory is not an endorsement.