NCT04076995

INDIGO-2: The Effect of High Water Intake on Glucose Regulation in Low-drinkers

• Status: Completed
• Phase: N/A
• Study type: Interventional
• Enrollment: 7 (actual)
• Sponsor: Arizona State University · Academic / Other
• Sex: All
• Age: 30 Years – 55 Years
• Healthy volunteers: Accepted

Summary

Previous studies have indicated increased vasopressin due to hypertonic saline infusion impairs glucose regulation. The current study will examine the effect of low water intake on glucose regulation. No currently published study has investigated the acute effect of low water intake on glucose regulation using continuous glucose monitoring over the course of a full day. The aim of the study is to observe the effect of low water intake on glucose regulation in low drinkers. The study will study the glycemic responses to standardized meals in adults during an 11-hour period in two conditions: a) high water intake and b) low water intake. It is hypothesized that the area under the glucose curve will be greater in the low water intake trial as compared to the high water intake trial

Conditions

• Dehydration
• Diabetes Mellitus, Type 2

Interventions

Type	Name	Description
OTHER	Water Intake	Increased water intake during the 11 h protocol

Timeline

• Start date: 2019-09-18
• Primary completion: 2019-12-19
• Completion: 2019-12-19
• First posted: 2019-09-04
• Last updated: 2020-02-11

Locations

1 site across 1 country: United States