NCT04075279

Heart at Work Study

Cardiovascular Mechanisms of the Occupational Physical Activity Health Paradox: 24-hour Physical Activity, Blood Pressure, and Heart Rate

• Status: Completed
• Phase: —
• Study type: Observational
• Enrollment: 19 (actual)
• Sponsor: University of Pittsburgh · Academic / Other
• Sex: Male
• Age: 35 Years – 59 Years
• Healthy volunteers: —

Summary

This is an observational study to examine the cardiovascular mechanisms of increased cardiovascular mortality in those with high activity occupations.

Detailed description

The current proposal uses a repeated-measures, within-subject design to address our aims. Twenty male participants will report to the laboratory to provide informed consent, complete baseline assessments, and receive ambulatory monitors. Following this session, each participant will wear physical activity and ambulatory cardiovascular monitors for 7 days, including at least one non-work day and one work day. Characterization of work activity will use physical activity data from self-reported time at work (Specific Aim I). The 24-hour cardiovascular load (HR and BP) and nocturnal HRV will be compared across work and non-work days (Specific Aim II). Lastly, whether fitness level or job strain modify the difference in cardiovascular strain between work vs. non-work days will be evaluated (Specific Aim III).

Conditions

• Occupational Diseases
• Cardiovascular Diseases
• Cardiovascular Risk Factor
• Occupational Exposure

Timeline

• Start date: 2019-10-17
• Primary completion: 2020-04-20
• Completion: 2020-07-24
• First posted: 2019-08-30
• Last updated: 2021-05-03
• Results posted: 2021-05-03

Locations

1 site across 1 country: United States