NCT04074460

Volatile Anaesthesia and Perioperative Outcomes Related to Cancer Feasibility Study

Volatile Anaesthesia and Perioperative Outcomes Related to Cancer (VAPOR-C): A Feasibility Study

• Status: Completed
• Phase: Phase 4
• Study type: Interventional
• Enrollment: 169 (actual)
• Sponsor: Peter MacCallum Cancer Centre, Australia · Academic / Other
• Sex: All
• Age: 18 Years – 80 Years
• Healthy volunteers: Not accepted

Summary

A multicentre, prospective randomized, active-controlled feasibility trial of volatile-based anaesthesia vs. propofol-based total intravenous anaesthesia to investigate the impact of anaesthesia on long-term (i.e. 5-years) patient cancer outcomes in patients undergoing elective major cancer surgery.

Detailed description

This study aims to assess the feasibility of conducting a phase IV, multi-centre, single-blinded, randomized control trial (VAPOR-C (Main)). Primary aims To measure the ability to recruit eligible patients into the study. To measure the ability to successfully deliver each of the two anaesthetic techniques (volatile-based general anaesthesia and propofol-based anaesthesia) according to the research protocol.

Conditions

• Cancer, Breast
• Cancer Colorectal
• Cancer Prostate
• Cancer, Lung
• Cancer Melanoma Skin
• Cancer, Other

Interventions

Type	Name	Description
DRUG	Propofol	General Anaesthesia
DRUG	isoflurane, sevoflurane or desflurane	General Anaesthesia

Timeline

• Start date: 2017-08-27
• Primary completion: 2019-10-31
• Completion: 2020-06-30
• First posted: 2019-08-30
• Last updated: 2022-06-09

Locations

1 site across 1 country: Australia