Trials / Completed
CompletedNCT04072731
SREBP1 as a Potential Biomarker Promotes Cell Proliferation and Invasion in Thyroid Cancer
- Status
- Completed
- Phase
- —
- Study type
- Observational
- Enrollment
- 140 (actual)
- Sponsor
- People's Hospital of Zhengzhou University · Academic / Other
- Sex
- All
- Age
- 18 Years – 60 Years
- Healthy volunteers
- Accepted
Summary
In this study, the investigators detected the expression of SREBP1 in thyroid cancer tissues, explored the biological functions of SREBP1 in thyroid cancer cells.
Detailed description
qRT-PCR and immunohistochemistry were used to detect the expression of SREBP1 in 96 pairs thyroid cancer tissues and the adjacent normal tissues. The following methods, including the MTS, colony-forming assay, flow cytometry and hoechst staining were used to detect the biological function of thyroid cancer cells based on SREBP1 interference or not.
Conditions
Interventions
| Type | Name | Description |
|---|---|---|
| OTHER | pathologic | All the enrolled patients were treated with whole resection and diagnosed by the Pathology Department based on the pathological evidence. |
Timeline
- Start date
- 2016-01-16
- Primary completion
- 2017-07-30
- Completion
- 2018-01-01
- First posted
- 2019-08-28
- Last updated
- 2019-08-28
Locations
1 site across 1 country: China
Source: ClinicalTrials.gov record NCT04072731. Inclusion in this directory is not an endorsement.