NCT04069650

Malnutrition is Not a Risk Factor for Free Flap Failure in the Oral Cavity

• Status: Completed
• Phase: —
• Study type: Observational
• Enrollment: 70 (actual)
• Sponsor: Centre Hospitalier Universitaire Dijon · Academic / Other
• Sex: All
• Age: 18 Years
• Healthy volunteers: Not accepted

Summary

Free flap reconstruction consists in replacing tissular defect from one body part by another tissu harvested in a distant site. Microsurgery has to be performed to restore vascularization. Free flaps are now the gold standard in complex reconstruction. While reliable with a success rate superior to 95 %, a failure takes a heavy burden on the patient. Many risk factors have been highlitghted in free flap failure for head and neck microvascular reconstruction. Among them, malnutrition is still debated. This is a retrospective cohort study comparing complications occurrence between two groups. One group with normal nutritionnal status, the other with malnutrition. Between january 2008 and january 2018, 70 patients who underwent oral cavity reconstruction using free flap were included. This is the first study known to date which uses clinical and biological variables to determine the nutritionnal status. Malnutrition is not associated with a higher risk for free flap failure in the oral cavity.

Conditions

• Free Flap Reconstruction

Interventions

Type	Name	Description
PROCEDURE	Free flap	Free flap reconstruction of the oral cavity

Timeline

• Start date: 2018-02-01
• Primary completion: 2018-05-31
• Completion: 2018-06-30
• First posted: 2019-08-28
• Last updated: 2019-08-28

Locations

1 site across 1 country: France