Clinical Trials Directory

Trials / Completed

CompletedNCT04069156

The ARIES HeartMate 3 Pump IDE Study

Antiplatelet Removal and HemocompatIbility EventS With the HeartMate 3 Pump IDE Study

Status
Completed
Phase
N/A
Study type
Interventional
Enrollment
628 (actual)
Sponsor
Abbott Medical Devices · Industry
Sex
All
Age
18 Years
Healthy volunteers
Not accepted

Summary

Prospective, randomized, double-blinded, placebo-controlled clinical investigation of advanced heart failure patients treated with the HM3 with two different antithrombotic regimens: vitamin K antagonist with aspirin versus vitamin K antagonist with placebo

Detailed description

This clinical investigation is a prospective, randomized, double-blinded, placebo-controlled study of advanced heart failure patients treated with the HM3 with two different antithrombotic regimens: vitamin K antagonist with aspirin versus vitamin K antagonist with placebo.

Conditions

Interventions

TypeNameDescription
DEVICELVAD ImplantSubjects will undergo Heartmate 3 LVAD implant prior to randomization
DRUGAspirin 100mgSubjects will be randomized to either Placebo or Aspirin post implant.
DRUGPlacebo oral tabletSubjects will be randomized to either Placebo or Aspirin post implant

Timeline

Start date
2020-07-14
Primary completion
2023-08-10
Completion
2023-08-10
First posted
2019-08-28
Last updated
2025-03-27
Results posted
2025-03-27

Locations

51 sites across 9 countries: United States, Australia, Austria, Canada, Czechia, France, Italy, Kazakhstan, United Kingdom

Regulatory

Source: ClinicalTrials.gov record NCT04069156. Inclusion in this directory is not an endorsement.