NCT04068389

Ultrafine Particles and Fetal Contamination

Study of the Permeability of Atmospheric Particles Placenta (Fine and Ultrafine Particles): Analysis of Fetal Retention

• Status: Completed
• Phase: —
• Study type: Observational
• Enrollment: 62 (actual)
• Sponsor: University Hospital, Bordeaux · Academic / Other
• Sex: Female
• Age: —
• Healthy volunteers: —

Summary

The objective of this study is to evaluate the transplacental passage of fine and ultrafine particles (nanoparticles) inhaled by the mother.

Detailed description

Epidemiological studies have demonstrated the harmful effects of particulate air pollution on the progress of pregnancy and postnatal health. Experimental studies have suggested the transplacental passage of asbestos fibers, but despite the strong growth in the use and production of fine and ultrafine particles, no study has examined the permeability of the placenta to these compounds or the exposures fetuses that may result. The objective of this study is to evaluate the transplacental passage of fine and ultrafine particles (nanoparticles) inhaled by the mother.

Conditions

• Lung; Premature
• Pollution; Exposure

Interventions

Type	Name	Description
PROCEDURE	Pulmonary Tissue Collection	Pulmonary Tissue Collection

Timeline

• Start date: 2009-12-22
• Primary completion: 2012-11-09
• Completion: 2012-11-09
• First posted: 2019-08-28
• Last updated: 2019-08-28