NCT04066842

Vitamin D in Systemic Sclerosis Patients With Periodontitis

Evaluation Of Vitamin D In Systemic Sclerosis Patients With Periodontitis: A Possible Role In Cardiovascular Disease Risk Progression?

• Status: Completed
• Phase: —
• Study type: Observational
• Enrollment: 168 (actual)
• Sponsor: University of Messina · Academic / Other
• Sex: All
• Age: 20 Years – 75 Years
• Healthy volunteers: Accepted

Summary

Vitamin D has been considered to possess anti-inflammatory and antimicrobial activity which may be a link for the known interaction of Systemic Sclerosis (SSc) and coronary heart disease (CHD). This study investigated the association between serum vitamin D levels and SSc and periodontitis in patients with SSc, CP and with CHD. Furthermore, the objective was to determine if periodontitis and CHD had an impact on serum vitamin D levels.

Detailed description

Using a cross-sectional design, a total of 42 patients with SSc, 43 patients with CHD, 41 patients with both SSc and CP, and 42 healthy patients were enrolled in the present study.

Conditions

• Vitamin D Deficiency

Interventions

Type	Name	Description
OTHER	Observation	Evaluation of Vitamin D levels and correlation of Vitamin D levels level with periodontal and cardiovascular disease

Timeline

• Start date: 2015-11-01
• Primary completion: 2019-05-15
• Completion: 2019-05-30
• First posted: 2019-08-26
• Last updated: 2019-08-26

Locations

1 site across 1 country: Italy