NCT04066478

Does DHEA IVF Outcomes in Poor Responders?

Does Dehydroepiandrosterone (DHEA) Improve IVF Outcomes in Poor Responders? A Randomised, Double-blind, Placebo Controlled Trial

• Status: Suspended
• Phase: Phase 2 / Phase 3
• Study type: Interventional
• Enrollment: 400 (estimated)
• Sponsor: Homerton University Hospital NHS Foundation Trust · Academic / Other
• Sex: Female
• Age: 40 Years – 42 Years
• Healthy volunteers: Not accepted

Summary

This study is a RCT to examine whether DHEA is capable of improving results for poor responders to ovarian stimulation during IVF treatment

Detailed description

Poor responders to ovarian stimulation for IVF may be either predicted or evidenced from previous treatment. The ESHRE criteria for poor responders will be used to select candidates for this trial. A power calculation determined that 200 subjects should be recruited to each arm to receive either DHEA or placebo.

Conditions

• Infertility, Female
• Poor Response to Ovulation Induction

Interventions

Type	Name	Description
DRUG	Dehydroepiandrosterone	75mg Dehydroepiandrosterone daily
DRUG	Placebo	Placebo

Timeline

• Start date: 2017-10-08
• Primary completion: 2022-12-31
• Completion: 2022-12-31
• First posted: 2019-08-26
• Last updated: 2022-06-23

Locations

1 site across 1 country: United Kingdom