NCT04066257

Evaluate the PK of Multiple Oral Doses of Tegoprazan, Metronidazole, Tetracycline and Bismuth in Healthy Volunteers

An Open-Label, Randomized, Crossover Study to Evaluate the Pharmacokinetic Interaction After Multiple Oral Doses of Tegoprazan, Metronidazole, Tetracycline and Bismuth in Healthy Volunteers

• Status: Completed
• Phase: Phase 1
• Study type: Interventional
• Enrollment: 32 (actual)
• Sponsor: HK inno.N Corporation · Industry
• Sex: All
• Age: 19 Years – 55 Years
• Healthy volunteers: Accepted

Summary

This study aims to evaluate the pharmacokinetic interaction between tegoprazan and combination of metronidazole, tetracycline and bismuth in healthy adult volunteers.

Detailed description

A open-label, randomized, multiple dose, two arm, two period, crossover study

Conditions

• Healthy

Interventions

Type	Name	Description
DRUG	Tegoprazan	Tegoprazan 50 mg tablet
DRUG	Metronidazole	Metronidazole 250 mg tablet
DRUG	Tetracycline	Tetracycline hydrochloride 250 mg capsule
DRUG	Bismuth	Tripotassium bismuth dicitrate 300 mg tablet

Timeline

• Start date: 2019-01-17
• Primary completion: 2019-02-22
• Completion: 2019-04-25
• First posted: 2019-08-26
• Last updated: 2019-08-28

Locations

1 site across 1 country: South Korea