Clinical Trials Directory

Trials / Completed

CompletedNCT04065581

Bioequivalence Study for Acarbose/Metformin FDC

Randomized, Non-blinded Crossover Study to Establish the Bioequivalence Between Fixed Dose Combination (FDC) and the Loose Combination of Acarbose and Metformin Following Single Oral Dosing in Chinese Healthy Adult Male and Female Subjects

Status
Completed
Phase
Phase 1
Study type
Interventional
Enrollment
24 (actual)
Sponsor
Bayer · Industry
Sex
All
Age
18 Years
Healthy volunteers
Accepted

Summary

The purpose of this study is to establish the bioequivalence (i.e. similar pharmacokinetics and pharmacodynamics characteristics) between acarbose/metformin FDC (50 mg/500 mg) and loose combination of acarbose (50 mg) and metformin (500 mg)

Conditions

Interventions

TypeNameDescription
DRUGAcarbose/Metformin FDC(BAY81-9783)Single dose: 50 mg acarbose/500 mg metformin tablet, oral
DRUGGlucobaySingle dose: 50 mg tablet, oral
DRUGGlucophageSingle dose: 500 mg tablet, oral

Timeline

Start date
2019-10-14
Primary completion
2019-11-25
Completion
2020-03-06
First posted
2019-08-22
Last updated
2020-04-13

Locations

1 site across 1 country: China

Source: ClinicalTrials.gov record NCT04065581. Inclusion in this directory is not an endorsement.

Bioequivalence Study for Acarbose/Metformin FDC (NCT04065581) · Clinical Trials Directory