Clinical Trials Directory

Trials / Unknown

UnknownNCT04063345

Long-term Clinical Outcomes of intraVascular Ultrasound-guided vs Angiography-guided Primary pErcutaneous Intervention in Patients With Acute ST Segment Elevated Myocardial Infarction

A Prospective, Open Label, Multicenter and Randomized Study of Clinical Outcomes of Intravascular Ultrasound -Guided and Angiography-Guided Primary Percutaneous Intervention in Patients With Acute ST Segment Elevated Myocardial Infarction

Status
Unknown
Phase
Phase 2 / Phase 3
Study type
Interventional
Enrollment
200 (estimated)
Sponsor
Second Affiliated Hospital, School of Medicine, Zhejiang University · Academic / Other
Sex
All
Age
18 Years
Healthy volunteers
Not accepted

Summary

To examine the impact of IVUS guidance on clinical outcomes in the patient with Acute ST Segment Elevated Myocardial Infarction.

Detailed description

Intravascular ultrasound (IVUS) has been increasingly used as a guide for percutaneous coronary intervention (PCI) during elective as well as emergent clinical scenario. Recent small number randomized studies, large scale registries as well as meta-analysis have consistently demonstrated advantages of IVUS-guidance over angiography-guide alone with respect to the lower incident of death, myocardial infarction and target vessel revascularization. There are sparse data available on the clinical impact of IVUS-guided PCI in the setting of acute myocardial infarction (AMI) and its use remains a matter of controversy as shown by previous studies. This study is to examine the impact of IVUS guidance on clinical outcomes in the patient with Acute ST Segment Elevated Myocardial Infarction (STEMI).

Conditions

Interventions

TypeNameDescription
PROCEDUREIVUS-guided PCIPerforming intravascular ultrasound before or/and after percutaneous intervention
PROCEDUREAngiography-guided PCIPerforming percutaneous intervention without intravascular ultrasound guidance

Timeline

Start date
2021-10-01
Primary completion
2022-10-01
Completion
2023-10-01
First posted
2019-08-21
Last updated
2021-01-29

Locations

1 site across 1 country: China

Source: ClinicalTrials.gov record NCT04063345. Inclusion in this directory is not an endorsement.