NCT04062955

Effects of Alternative Healthy Eating Index-Based Diet on Inflammatory Markers and Breast Density in Healthy Participants

Adherence to the Alternative Healthy Eating Index and Effects on Inflammatory Markers and Breast Density

• Status: Completed
• Phase: N/A
• Study type: Interventional
• Enrollment: 21 (actual)
• Sponsor: Fred Hutchinson Cancer Center · Academic / Other
• Sex: Female
• Age: 18 Years – 50 Years
• Healthy volunteers: Accepted

Summary

This trial studies the effects of a dietary intervention based on the Alternative Healthy Eating Index (AHEI) on inflammatory markers and breast density in healthy participants. The AHEI is a quantifiable measure of diet quality designed to target food and macronutrient sources that are associated with chronic disease risk. Adherence to the AHEI may be associated with a reduction in inflammatory biomarkers and sex steroid hormone levels compared to other dietary patterns/scores.

Detailed description

OUTLINE: DIETARY INTERVENTION: Participants receive dietary counseling with a dietitian in person or via telephone to support adherence to a diet based on the AHEI guidelines once weekly for up to 12 weeks. DUAL X-RAY ABSORPTIOMETRY (DXA) ONLY STUDY: Participants undergo DXA scan for breast density measurement at baseline and at 12 weeks.

Conditions

• Healthy Subject

Interventions

Type	Name	Description
DIETARY_SUPPLEMENT	Dietary Intervention	Receive dietary counseling
PROCEDURE	Dual X-ray Absorptiometry	Undergo DXA scan
OTHER	Questionnaire Administration	Ancillary studies

Timeline

• Start date: 2019-10-28
• Primary completion: 2020-11-19
• Completion: 2020-11-19
• First posted: 2019-08-20
• Last updated: 2021-01-22

Locations

1 site across 1 country: United States