NCT04057027

The Effect of Delayed Cord Clamping and Milking on the Amount of Stem Cells In Preterm

The Effect of Delayed Cord Clamping and Milking on the Amount of Endogenous Stem Cells In Preterm Infants

• Status: Unknown
• Phase: N/A
• Study type: Interventional
• Enrollment: 90 (estimated)
• Sponsor: Kanuni Sultan Suleyman Training and Research Hospital · Academic / Other
• Sex: All
• Age: 30 Minutes
• Healthy volunteers: Accepted

Summary

Stem cell therapies have been promising therapies in neonatal morbidities such as bronchopulmonary dysplasia, intraventricular hemorrhage and hypoxic ischemic encephalopathy. Although researchers showed those effects by several mechanisms including paracrine effect, regenerative and restorative effects, there is no obvious recommendations for the type of stem cells, dosage or the route of administration the cells. The usage of exogenous stem cells can be difficult due to technical issues in preterm infants. In the presence of these data, the amount of endogenous stem cells passing through the cord to the infant may show differences in terms of delayed cord clamping and milking. Therefore the aim of this prospective randomized study is to determine the quantity of the stem cells according to delayed cord clamping or cord milking. We also aimed to evaluate the association between the number of stem cells and neonatal morbidities.

Conditions

• Umbilical Cord; Clamping Time

Interventions

Type	Name	Description
PROCEDURE	Delayed umbilical cord clamping	During the C section, infants' umbilical cord clamping will be delayed for 30-60 seconds.
PROCEDURE	Cord Milking	Umbilical cord will be milked from th distance of 20cm from mother's side to the baby, for 3-4 times.

Timeline

• Start date: 2019-09-15
• Primary completion: 2020-09-05
• Completion: 2020-10-01
• First posted: 2019-08-14
• Last updated: 2020-05-07

Locations

1 site across 1 country: Turkey (Türkiye)