NCT04055194

Antenatal Tranexamic Acid in Women With Symptomatic Placenta Previa

Efficacy of Antenatal Tranexamic Acid in Pregnant Women With Symptomatic Placenta Previa in Decreasing Antepartum Hemorrhage - A Randomized Controlled Trial

• Status: Unknown
• Phase: Phase 2 / Phase 3
• Study type: Interventional
• Enrollment: 200 (estimated)
• Sponsor: Ain Shams University · Academic / Other
• Sex: Female
• Age: 20 Years – 40 Years
• Healthy volunteers: Not accepted

Summary

200 pregnant women with symptomatic placenta previa with previous bleeding attacks attending Ain Shams University maternity hospital will be recruited and randomized to receive either tranexamic acid tablets (500mg four times daily) or placebo. Amount of bleeding during antepartum bleeding attacks will be estimated (by hemoglobin change from baseline at admission till delivery).

Conditions

• Placenta Previa

Interventions

Type	Name	Description
DRUG	Tranexamic acid tablets	Pregnant women with symptomatic placenta previa with previous bleeding attacks will receive tranexamic acid tablets (500mg four times daily) till delivery.
DRUG	Placebo oral tablet	Pregnant women with symptomatic placenta previa with previous bleeding attacks will receive placebo tablets four times daily till delivery.

Timeline

• Start date: 2019-08-01
• Primary completion: 2020-07-01
• Completion: 2020-08-01
• First posted: 2019-08-13
• Last updated: 2019-08-13

Locations

1 site across 1 country: Egypt