NCT04053998

Benchmarking Outcomes in Pancreatic Surgery - WhippleBenchmarks.Org

Benchmarking Outcomes in Pancreatoduodenectomy With Portal Vein Resection - WhippleBenchmarks.Org

• Status: Completed
• Phase: —
• Study type: Observational
• Enrollment: 1,462 (actual)
• Sponsor: Royal Free Hospital NHS Foundation Trust · Academic / Other
• Sex: All
• Age: 18 Years
• Healthy volunteers: Not accepted

Summary

The WhippleBenchmark 2 Collaborative study aims at defining benchmark criteria for best achievable outcomes after pancreaticoduodenectomy with portal vein resection.

Detailed description

Pancreatoduodenectomy (PD) with portal vein resection (PVR) is performed for the achievement of complete resection (R0) in patients with locally advanced pancreatic head lesions. Despite most commonly performed in high-volume pancreatic surgery centers by experienced surgeons, best achievable outcomes, such as morbidity and mortality, following such complex procedure remain unknown. The aim is to conduct a retrospective multicenter cohort study to define benchmark values for best achievable outcomes following duodenopancreatectomy (DP) with portal vein resection (PVR). Data collection and study design are based on to the well established standardized reporting for benchmarking (Sánchez-Velázquez et. al. Ann Surg, February 2019 ). This multicenter cohort study will include all consecutive pancreaticoduodenectomies with portal vein resections from at least 20 high volume centers performing over 50 pancreatic operations per year or 150 cases within 3 years from at least 3 continents over a period of 10 years (2009-2019). Every center included in the study must have a prospective database from which data can be collected as well as previous publications critically reporting on their outcome.

Conditions

• Pancreatic Neoplasms
• Pancreaticoduodenectomy

Interventions

Type	Name	Description
PROCEDURE	Pancreaticoduodenectomy with portal vein resection	Pancreatic surgery with vein resection to achieve disease clearance.

Timeline

• Start date: 2019-08-09
• Primary completion: 2020-02-10
• Completion: 2020-02-20
• First posted: 2019-08-13
• Last updated: 2020-11-20

Locations

2 sites across 2 countries: Spain, United Kingdom