NCT04053660

Effect Of Non-Surgical Periodontal Treatment On Lipoxin a4 Levels

Effect Of Non-Surgical Periodontal Treatment On Endogenous Anti-Inflammatory Lipid Mediators In Patients With Chronic Periodontitis

• Status: Completed
• Phase: N/A
• Study type: Interventional
• Enrollment: 20 (actual)
• Sponsor: Ordu University · Academic / Other
• Sex: All
• Age: 25 Years – 65 Years
• Healthy volunteers: Accepted

Summary

The aim of this study was to evaluate the levels of lipoxin A4 (LXA4), prostaglandin E2 (PGE2) and leukotriene B4 (LTB4) in gingival crevicular fluid (GCF) and saliva in individuals with periodontal healthy and chronic periodontitis. In addition, the investigators evaluated the levels of these mediators after non-surgical periodontal treatment in patients with chronic periodontitis. A total of 20 subjects, 10 patients with chronic periodontitis (CP) and 10 periodontally healthy individuals were included in the study. Clinical parameters including plaque index (PI), gingival index (GI), probing depth (PD) and clinical attachment levels (CAL) were recorded. GCF and saliva samples were obtained at the beginning of the study from all individuals. GCF and saliva samples were re-collected from patients with CP at 1 month after non surgical periodontal therapy.

Conditions

• Periodontitis

Interventions

Type	Name	Description
PROCEDURE	Non-surgical periodontal treatment	Mechanical non-surgical treatment were performed

Timeline

• Start date: 2017-10-01
• Primary completion: 2018-12-31
• Completion: 2018-12-31
• First posted: 2019-08-12
• Last updated: 2019-08-12

Locations

1 site across 1 country: Turkey (Türkiye)