Clinical Trials Directory

Trials / Completed

CompletedNCT04051606

Regorafenib in Bevacizumab Refractory Recurrent Glioblastoma

Status
Completed
Phase
Phase 2
Study type
Interventional
Enrollment
14 (actual)
Sponsor
Case Comprehensive Cancer Center · Academic / Other
Sex
All
Age
18 Years
Healthy volunteers
Not accepted

Summary

The purpose of this study is to determine the safety and tolerability of Regorafenib in patients with recurrent or progressive glioblastoma (GBM) who have progressed on bevacizumab. Regorafenib is FDA approved administered as monotherapy during the study. 22 total patients are expected to participate in this study. Even though a participant may meet all the criteria for participation, it is possible that they will not be enrolled in this study.

Conditions

Interventions

TypeNameDescription
DRUGRegorafenibRegorafenib is a monotherapy during the study, oral administration at 160 mg once daily will be administered for 3 weeks on /1 week off.

Timeline

Start date
2019-07-31
Primary completion
2024-03-20
Completion
2024-03-20
First posted
2019-08-09
Last updated
2025-06-05

Locations

1 site across 1 country: United States

Source: ClinicalTrials.gov record NCT04051606. Inclusion in this directory is not an endorsement.