NCT04051099

Bilateral Superficial Cervical Plexus Block in Thyroid/Parathyroid Surgery

Bilateral Superficial Cervical Plexus Block Combined With Intravenous Sedation Versus General Anesthesia in Selected Patients for Thyroid/Parathyroid Surgery ; a Prospective Randomized Control Trial

• Status: Unknown
• Phase: N/A
• Study type: Interventional
• Enrollment: 52 (estimated)
• Sponsor: Mahidol University · Academic / Other
• Sex: All
• Age: 18 Years
• Healthy volunteers: Not accepted

Summary

To compare efficacy and safety between bilateral superficial cervical plexus block combined with intravenous sedation (RA group) and general anesthesia (GA group) for thyroid and parathyroid operations. This study evaluates postoperative numerical pain score and systemic opioid requirement within 24 hours.

Detailed description

According to literature review, there is limit information about efficacy and safety of thyroid and parathyroid operations under bilateral superficial cervical plexus block combined with intravenous sedation without general anesthesia. General anesthesia is commonly used for neck operations because it is easy to perform. However in high cardiovascular or pulmonary risk patients such as end stage renal disease (ESRD) patients, regional anesthesia such as superficial cervical plexus block combined with intravenous sedation have become an alternative technique for neck operations. This study evaluate whether regional anesthesia (RA) technique can be the alternative technique for thyroid/parathyroid surgery compare to conventional technique (GA).

Conditions

• Benign Tumor of Thyroid
• Hyperparathyroidism

Interventions

Type	Name	Description
PROCEDURE	Bilateral superficial cervical plexus block with 0.25% bupivacaine 8 ml each (total 16 ml)	bilateral superficial cervical plexus
DRUG	Dexmedetomidine plus propofol infusion	Dexmedetomidine 0.5 ug/kg infusion in 10 min then 0.5 ug/kg/h, Propofol infusion
PROCEDURE	Local infiltraion analgesia	local infiltration analgesia with 2%lidocaine with adrenaline 5 ug/ml 10 ml
PROCEDURE	General anesthesia with endotracheal tube	Induction with Propofol and intubation with cisatracurium

Timeline

• Start date: 2018-03-01
• Primary completion: 2021-09-30
• Completion: 2021-12-15
• First posted: 2019-08-09
• Last updated: 2021-05-24

Locations

1 site across 1 country: Thailand