NCT04049461

Heterotopic Ossification in Abdominal Incision and Pancreatic Cancer

The Causes of Heterotopic Ossification in Abdominal Incision After Pancreatic Surgery：A Single-center Prospective Study

• Status: Unknown
• Phase: —
• Study type: Observational
• Enrollment: 105 (estimated)
• Sponsor: Nanjing Medical University · Academic / Other
• Sex: All
• Age: 18 Years – 80 Years
• Healthy volunteers: Not accepted

Summary

To investigate whether pancreatic cancer is the cause of heterotopic ossification of abdominal incision.

Detailed description

Heterotopic ossification of abdominal incision (HOAI) has long been regarded as a rare complication after general surgery. However,according to our retrospective analysis. HOAI was more frequently observed in the malignancy group (33/121 cases, 27.3%) than in the non- malignancy group. Because of the many biases in the retrospective analysis, the result was not widely shared. The purpose of this prospective study is to confirm that pancreatic cancer is the cause of heterotopic ossification of abdominal incisions. According to postoperative pathology, the patients were divided into two groups: pancreatic cancer group and benign diseases group.The researchers will observe whether patients develop heterotopic ossification of the abdominal incision one year after surgery to conclude.

Conditions

• Cancer of Pancreas
• Ossification, Heterotopic

Interventions

Type	Name	Description
DIAGNOSTIC_TEST	Bone alkaline phosphatase	Hematologic indicators reflecting ossification.
RADIATION	Abdominal CT scan	Observe whether HOAI occurs.

Timeline

• Start date: 2019-09-01
• Primary completion: 2020-12-31
• Completion: 2025-12-31
• First posted: 2019-08-08
• Last updated: 2019-08-08

Locations

1 site across 1 country: China