Trials / Completed
CompletedNCT04046861
Influence of High Vitamin C Dose on Lactate During and After Extracorporeal Circulation
"Influence of High Vitamin C Dose on Lactate During Extracorporeal Circulation for Heart Surgery and During the 24 Hours Thereafter." (double Blind Prospective Randomised Study)
- Status
- Completed
- Phase
- N/A
- Study type
- Interventional
- Enrollment
- 70 (actual)
- Sponsor
- University Medical Centre Maribor · Academic / Other
- Sex
- All
- Age
- 18 Years – 100 Years
- Healthy volunteers
- Not accepted
Summary
The aim of our study is to find out whether high doses of vitamin C before cardiopulmonary bypass and during the first 24 hours after that have and impact of lowering the incidence of hyperlactatemia.
Conditions
Interventions
| Type | Name | Description |
|---|---|---|
| DIETARY_SUPPLEMENT | ascorbic acid, | The vitamin C group will get high dose of intravenous vitamin C (ascorbic acid) before starting cardiopulmonary bypass, before removing aortic clamp and every 8 hours thereafter for additionaly 24 hours |
| OTHER | Placebo (saline) | The placebo group will get saline before starting cardiopulmonary bypass, before removing aortic clamp and every 8 hours thereafter for additionaly 24 hours |
Timeline
- Start date
- 2023-03-01
- Primary completion
- 2023-12-01
- Completion
- 2024-09-01
- First posted
- 2019-08-06
- Last updated
- 2025-02-21
Locations
1 site across 1 country: Slovenia
Source: ClinicalTrials.gov record NCT04046861. Inclusion in this directory is not an endorsement.