NCT04041622

Coeliac Disease in the Nord-Trøndelag Health Study (HUNT)

• Status: Completed
• Phase: N/A
• Study type: Interventional
• Enrollment: 56,000 (actual)
• Sponsor: Norwegian University of Science and Technology · Academic / Other
• Sex: All
• Age: 20 Years
• Healthy volunteers: Accepted

Summary

In this study, all citizen of Nord-Trøndelag County, Norway, above 20 years of age are invited to participate in a population-based health study, the HUNT study. Blood samples are drawn from the participants and assessed for celiac disease by a serological assay. Celiac disease is a chronic inflammatory disease of the small intestine due to dietary gluten in wheat, barley and rye. The diagnosis will be verified through endoscopic assessment and biopsies from the small intestinal mucosa. The aims of the study are 1) to establish the population-based prevalence of celiac disease; 2) to assess the consequences of the disease from patient reported outcomes, symptoms, deficiencies, and co-morbidity; 3) to study possible risk factors and environmental triggering events; 4) to identify genetic predictors and gene-environmental interactions.

Conditions

• Celiac Disease

Interventions

Type	Name	Description
DIAGNOSTIC_TEST	Endoscopy and biopsy	Participants with a positive celiac serology are assessed by endoscopy and duodenal biopsy

Timeline

• Start date: 2019-06-17
• Primary completion: 2024-07-01
• Completion: 2024-07-01
• First posted: 2019-08-01
• Last updated: 2025-05-25

Locations

1 site across 1 country: Norway