NCT04040946

Trial Comparing 2 Diagnostic Strategies for Preoperative Localization of Parathyroid Adenoma in Primary Hyperparathyroidism:TEMP / CT With Tc99m-sestaMIBI or PET / CT With F18-choline in First Intention

Phase III Trial Comparing 2 Diagnostic Strategies for Preoperative Localization of Parathyroid Adenoma in Primary Hyperparathyroidism:TEMP / CT With Tc99m-sestaMIBI or PET / CT With F18-choline in First Intention

• Status: Completed
• Phase: Phase 3
• Study type: Interventional
• Enrollment: 59 (actual)
• Sponsor: Centre Francois Baclesse · Academic / Other
• Sex: All
• Age: 18 Years
• Healthy volunteers: Not accepted

Summary

The investigators hypothesize that positron emission tomography with fluorocholline (F18-choline PET) will reduce the proportion of unnecessary invasive surgery decisions and that the higher cost of positron emission tomography versus MIBI scintigraphy (Tc99m-sestaMIBI ) will be offset by lower cost in terms of type. surgery performed wisely and complications.

Conditions

• Parathyroid Adenoma
• Hyperparathyroidism
• F18-choline

Interventions

Type	Name	Description
DIAGNOSTIC_TEST	MIBI scintigraphy	Performing a MIBI scintigraphy, then, in the case of negativity, a single F18-choline PET
DIAGNOSTIC_TEST	F18-choline PET	Realization of a F18-choline PET, then, in case of negativity, a MIBI scintigraphy

Timeline

• Start date: 2019-09-19
• Primary completion: 2022-05-05
• Completion: 2023-06-30
• First posted: 2019-08-01
• Last updated: 2023-08-01

Locations

4 sites across 1 country: France