Clinical Trials Directory

Trials / Terminated

TerminatedNCT04039919

A Study to Test the Pharmacodynamic, Pharmacokinetic, Safety, and Tolerability of Padsevonil in Healthy Study Participants Receiving Either Ethanol or Cannabidiol

A Double-Blind, Placebo-Controlled, Randomized, Single-Center, Cross-Over Study to Investigate the Pharmacodynamic, Pharmacokinetic, Safety, and Tolerability Profiles of Padsevonil in Healthy Study Participants Receiving Either Ethanol or Cannabidiol

Status
Terminated
Phase
Phase 1
Study type
Interventional
Enrollment
40 (actual)
Sponsor
UCB Biopharma S.P.R.L. · Industry
Sex
All
Age
18 Years – 55 Years
Healthy volunteers
Accepted

Summary

The purpose of the study is to evaluate the pharmacodynamic (PD) interaction between steady-steady treatment with padsevonil (PSL) and Ethanol and the pharmacokinetic (PK) interaction between stead-state treatment with PSL and cannabidiol (CBD).

Conditions

Interventions

TypeNameDescription
DRUGPadsevonilPadsevonil will be administered in predefined dosages.
DRUGPlacebo (PSL)Placebo will be provided matching Padsevonil to maintain the blinding.

Timeline

Start date
2019-07-17
Primary completion
2020-05-22
Completion
2020-05-22
First posted
2019-07-31
Last updated
2021-06-18
Results posted
2021-06-18

Locations

1 site across 1 country: Netherlands

Source: ClinicalTrials.gov record NCT04039919. Inclusion in this directory is not an endorsement.